40s ribosomal protein s2
Nucleic Acids Res, 2020 Dec 16.
Manually curated information for which there is published experimental evidence.
As is typical for gene… We identified the 40S ribosomal protein S2 as the first physiological substrate of PRMT3. Sequence archive. Does not affect readthrough on the poly(A)-stall sequences; when associated with R-58. UniParc. RPS2: a ribosomal protein that is a component of the 40S subunit. 24:165-169(2014), Biochem Biophys Res Commun 335:146-153(2005), Proc. Some ribosomal proteins (RPs) play critical roles in regulating p53 by interacting with MDM2. This gene encodes a ribosomal protein that is a component of the 40S subunit. . Ribosomes are cellular macromolecules that catalyze protein synthesis across all kingdoms of life. Protein sets from fully sequenced genomes. Ribosomal protein S2 (Rps2p) is a conserved protein of the SSU and essential for the SSU synthesis in yeast since a complete inhibition of the SSU production due to loss of Rps2p (Perreault et al., 2008). of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.,A UniProt proteome can consist of several components.
The component name refers to the genomic component encoding a set of proteins.
This section provides information on the location and the topology of the mature protein in the cell.
,This section provides information on the disease(s) and phenotype(s) associated with a protein.
,This subsection of the 'Pathology and Biotech' section describes the effect of the experimental mutation of one or more amino acid(s) on the biological properties of the protein.
. The current subsections and their content are listed below:,This subsection of the Sequence section indicates if the canonical sequence displayed by default in the entry is complete or not.
,This subsection of the Sequence section indicates if the canonical sequence displayed by default in the entry is in its mature form or if it represents the precursor.
,The checksum is a form of redundancy check that is calculated Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.
,This section provides any useful information about the protein, mostly biological knowledge.
,The Gene Ontology (GO) project provides a set of hierarchical controlled vocabulary split into 3 categories:
,Inferred from Physical Interaction
Help pages, FAQs, UniProtKB manual, documents, news archive and Biocuration projects. Ribosomes, the organelles which catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Asymmetric arginine dimethylation by PRMT3 occurs at multiple sites in the Arg/Gly-rich region. In this study, we found that Ribosomal Protein S2 (RPS2) is a new regulator of MDM2-P53 signaling pathway to regulate p53 protein level. Mature ribosomes consist of a small (40S) and a large (60S) subunit. Proteomes. SIMILARITY: Belongs to the ribosomal protein S5P family. Proteomes. U.S.A. 111:12432-12437(2014). Protein sets from fully sequenced genomes. [3], "Human cDNA sequence homologous to the mouse LLRep3 gene family", "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences", "Ribosomal protein S2 is a substrate for mammalian PRMT3 (protein arginine methyltransferase 3)", "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)", "Mass spectrometric analysis of the human 40S ribosomal subunit: native and HCV IRES-bound complexes", https://www.wikidoc.org/index.php?title=40S_ribosomal_protein_S2&oldid=1524763, Creative Commons Attribution/Share-Alike License, This page was last edited 09:24, 10 January 2019 by wikidoc user. Manual assertion inferred from combination of experimental and computational evidencei, Manual assertion inferred from combination of experimental and computational evidencei, jPOST - Japan Proteome Standard Repository/Database, MassIVE - Mass Spectrometry Interactive Virtual Environment, PaxDb, a database of protein abundance averages across all three domains of life, ProteomicsDB: a multi-organism proteome resource, iPTMnet integrated resource for PTMs in systems biology context, MetOSite database of methionine sulfoxide sites. Sci. It is located in the cytoplasm. ,This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.
,This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding lipids, glycans and protein cross-links.
, Manual assertion inferred from combination of experimental and computational evidence,This subsection of the PTM / Processing section describes covalent linkages of various types formed between two proteins (interchain cross-links) or between two parts of the same protein (intrachain cross-links), except the disulfide bonds that are annotated in the 'Disulfide bond' subsection.
, Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin), Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1); alternate, Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternate, Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin); alternate,This subsection of the PTM/processing section describes post-translational modifications (PTMs). It is useful for tracking sequence updates.
Sequence archive.However UniProtKB may contain entries with identical sequences in case Jointly these subunits are composed of 4 RNA species and … It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. 40S ribosomal protein S2: Smed ID: SMED30003176: Length (bp) 844: Neoblast Clusters. Industrial & Scientific Hello, Sign in. from the sequence. Diseases associated with RPS2 include Retinitis Pigmentosa 36 and Cardiac Valvular Dysplasia, X-Linked . Protein: RS2_MOUSE 40S ribosomal protein S2. SEQUENCE CAUTION: Sequence=AAA40074.1; Type=Frameshift; Positions=24; GENE SYNONYMS: Llrep3 Rps4. Help. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.
,This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). As a member of the wwPDB, the RCSB PDB curates and annotates PDB data according to agreed upon standards. You are using a version of browser that may not display all the features of this website. Systems used to automatically annotate proteins with high accuracy: UniRule (Expertly curated rules) Sequence clusters. Amazon.com: 40S ribosomal protein S2 (RPS2), Bovine, ELISA Kit: Industrial & Scientific. Protein sets from fully sequenced genomes. High accuracy: UniRule ( Expertly curated rules ) protein knowledgebase Biochem Biophys Res Commun 335:146-153 ( 2005,... Pluripotent neoblasts and its early progenies relating to sequence, structure and function annotation score provides variety. 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